HPR

Gene Name		haptoglobin-related protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Spherical High-density Lipoprotein Particle Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Catalytic Activity Hemoglobin Binding
	Biological Process	Receptor-mediated Endocytosis Metabolic Process
Pathways		Scavenging of heme from plasma
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) LDL cholesterol ( 20686565) Liver enzyme levels (alkaline phosphatase) ( 22001757) Metabolite levels ( 22916037)
Protein-protein Interactions		3 interactors: APOA1 IGHM VKORC1
Entrez ID		3250
HPRD ID		00773
Ensembl ID		ENSG00000261701
Uniprot IDs		P00739
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Interleukin-1 Beta Secretion Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Negative Regulation Of Interleukin-1 Secretion High-density Lipoprotein Particle Clearance Protein Oxidation Vitamin K Metabolic Process Negative Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Blood Coagulation Hemostasis Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Regulation Of Intestinal Cholesterol Absorption Phospholipid Homeostasis Peptidyl-methionine Modification Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Phospholipid Efflux Regulation Of Cytokine Secretion Involved In Immune Response Peptidyl-glutamic Acid Carboxylation Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Regulation Of Body Fluid Levels Negative Regulation Of Interleukin-1 Beta Production Wound Healing Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway High-density Lipoprotein Particle Remodeling Glucocorticoid Metabolic Process Protein-lipid Complex Assembly Endothelial Cell Proliferation Reverse Cholesterol Transport Negative Chemotaxis Response To Wounding Negative Regulation Of Lipase Activity Regulation Of Interleukin-1 Beta Secretion Phosphatidylcholine Biosynthetic Process Response To Stress Antibacterial Humoral Response Positive Regulation Of Lipid Catabolic Process Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Antimicrobial Humoral Response Cholesterol Efflux Regulation Of Cdc42 Protein Signal Transduction Positive Regulation Of Fatty Acid Metabolic Process
Tagcloud ?		47d anchorage chemoprevention efficient enables equally exerted feulgen heterodimers hi hs ineffective insensitive isotypes lgd macroscopic marginal mxt polymorphic progestagen relates retinoids ru rxr tamoxifen transglutaminase triggering ttnpb weak