ACACB

Name	acetyl-CoA carboxylase beta
Structure
Interactors	4 interactors: HLCS PEX14 PRKAA2 USP7
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Cytosol Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex
	Molecular Function	Nucleotide Binding Catalytic Activity Acetyl-CoA Carboxylase Activity Protein Binding ATP Binding Biotin Binding Ligase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Acetyl-CoA Metabolic Process Pentose-phosphate Shunt Purine Nucleotide Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Acyl-CoA Metabolic Process Response To Nutrient Response To Xenobiotic Stimulus Positive Regulation Of Lipid Storage Regulation Of Glucose Metabolic Process Fatty Acid Oxidation Response To Nutrient Levels Negative Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Fatty Acid Oxidation D-glucose Import Lactic Acid Secretion Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Fatty Acid Homeostasis Positive Regulation Of Heart Growth Response To Caloric Restriction Tricarboxylic Acid Metabolic Process Intracellular Aspartate Homeostasis Intracellular Glutamate Homeostasis Energy Homeostasis Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Malonyl-CoA Biosynthetic Process
Pathways	ChREBP activates metabolic gene expression Biotin transport and metabolism Carnitine shuttle Activation of gene expression by SREBF (SREBP)
Drugs	Biotin Adenine Soraphen A 2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid Haloxyfop-P
GWAS	Fish- and plant-related diet ( 32066663 ) Invasive cervical cancer ( 33794208 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Oily fish consumption ( 32066663 ) Pork consumption ( 32066663 ) Triglyceride levels ( 32203549 ) Triglycerides ( 30275531 )
Entrez ID	32
HPRD ID	07044
Ensembl ID	ENSG00000076555
Uniprot IDs	O00763
PDB IDs	2DN8 2HJW 2KCC 3FF6 3GID 3GLK 3JRW 3JRX 3TDC 4HQ6 5KKN
GO Terms Enriched among Interactors ?	Post-translational Protein Modification Protein Modification Process Response To Nutrient Levels Negative Regulation Of TORC1 Signaling TORC1 Signaling Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Peroxisome Transport Along Microtubule Protein Modification By Small Protein Conjugation Protein Ubiquitination Regulation Of TORC1 Signaling Regulation Of Circadian Rhythm Negative Regulation Of TOR Signaling TOR Signaling Response To Biotin Regulation Of TOR Signaling [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Histone H2BS36 Kinase Activity Biotin Metabolic Process Protein Metabolic Process Protein Import Into Peroxisome Matrix, Translocation Regulation Of DNA-binding Transcription Factor Activity Cellular Response To Oxidative Stress Protein Import Into Peroxisome Matrix, Docking Peroxisomal Importomer Complex Positive Regulation Of Autophagy Protein Localization To Lipid Droplet Symbiont-mediated Disruption Of Host Cell PML Body Biotin Binding Protein Import Into Peroxisome Matrix, Substrate Release Negative Regulation Of Hepatocyte Apoptotic Process Rhythmic Process Negative Regulation Of Tubulin Deacetylation Cellular Response To Nutrient Levels AMP-activated Protein Kinase Activity Regulation Of Establishment Of Protein Localization To Telomere Cellular Response To Chemical Stress Lipid Droplet Disassembly Regulation Of Tubulin Deacetylation Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Retrograde Transport, Endosome To Golgi Monoubiquitinated Protein Deubiquitination Regulation Of Small Molecule Metabolic Process Protein Import Into Peroxisome Matrix, Receptor Recycling Phosphatidylethanolamine Biosynthetic Process Response To Oxidative Stress Regulation Of Protein Deacetylation Nucleotide-activated Protein Kinase Complex Regulation Of Stress Granule Assembly DNA Alkylation Repair Protein Unfolding