ZNF354C

Description		zinc finger protein 354C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane Nuclear Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Sprouting Angiogenesis
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		A body shape index ( 34021172) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Depression in response to interferon-based therapy in chronic hepatitis C ( 27723809) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		7 interacting genes: CCDC6 LHX3 LHX4 LINC00624 LMO1 SRY TRIM28
Entrez ID		30832
HPRD ID		15785
Ensembl ID		ENSG00000177932
Uniprot IDs		Q86Y25
PDB IDs
Enriched GO Terms of Interacting Partners?		Medial Motor Column Neuron Differentiation Motor Neuron Axon Guidance Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cell Differentiation In Spinal Cord Placenta Development Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Prolactin Secreting Cell Differentiation Krueppel-associated Box Domain Binding Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin-like Protein Ligase Activity Positive Regulation Of Biosynthetic Process Ventral Spinal Cord Interneuron Specification Somatotropin Secreting Cell Differentiation Embryonic Placenta Morphogenesis DNA-binding Transcription Factor Binding Thyroid-stimulating Hormone-secreting Cell Differentiation Convergent Extension Involved In Axis Elongation Chromo Shadow Domain Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Male Gonad Development Spinal Cord Motor Neuron Cell Fate Specification Neuron Projection Guidance Axon Guidance Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Spinal Cord Association Neuron Differentiation Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Convergent Extension Transcription Coactivator Activity DNA Binding Male Sex Determination Regulation Of Nucleobase-containing Compound Metabolic Process Suppression Of Viral Release By Host DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Neuroendocrine Cell Differentiation Neuron Differentiation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding SUMO Transferase Activity Genomic Imprinting Sex Determination
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