HIST1H1E

Gene Name		histone cluster 1, H1e
Image
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nuclear Heterochromatin Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Chromatin DNA Binding Poly(A) RNA Binding
	Biological Process	Nucleosome Assembly Nucleosome Positioning
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CBX1 CBX3 CBX5 IL7R IRAK4 PRKCA
Entrez ID		3008
HPRD ID		07513
Ensembl ID		ENSG00000168298
Uniprot IDs		A3R0T8 P10412
PDB IDs		3TZD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Positive Regulation Of Dense Core Granule Biogenesis Response To Cytokine Interleukin-7-mediated Signaling Pathway Histone H3-T6 Phosphorylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Negative Regulation Of T Cell Mediated Cytotoxicity Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Glucose Import Immune Response Regulation Of Immune System Process Positive Regulation Of Macrophage Differentiation Negative Regulation Of Gene Expression Desmosome Organization Negative Regulation Of T Cell Mediated Immunity Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Blood Coagulation Hemostasis Positive Regulation Of Blood Vessel Endothelial Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Regulation Of Cell Activation Negative Regulation Of Lyase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Activation Of Adenylate Cyclase Activity Regulation Of Cardiac Muscle Hypertrophy Rhodopsin Mediated Signaling Pathway Regulation Of Platelet Activation Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Positive Chemotaxis Negative Regulation Of CAMP Metabolic Process Regulation Of The Force Of Heart Contraction Cellular Response To Organic Substance
Tagcloud ?		abundance arrest bax bcl beneficial calcitriol candidates changing cyclins d3 eif2ak2 endometrial g0 hint2 identifies immortalized investigates oncogenesis p27 preventing progesterone proteomics prove stranded triad upregulate validation