GZMM

Gene Name		granzyme M (lymphocyte met-ase 1)
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Gene Ontology Annotations	Cellular Component	Extracellular Region Membrane
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Proteolysis Apoptotic Process Cytolysis Innate Immune Response
Pathways		Alternative complement activation Complement cascade Initial triggering of complement Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: DFFA EZR NPM1 PARP1 TUBA1B
Entrez ID		3004
HPRD ID		02633
Ensembl ID		ENSG00000197540
Uniprot IDs		P51124
PDB IDs		1LZP 2ZGC 2ZGH 2ZGJ 2ZKS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic DNA Fragmentation Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Regulation Of Growth Rate Protein Poly-ADP-ribosylation Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity DNA Metabolic Process Membrane To Membrane Docking Cytoskeleton Organization Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Organelle Organization Regulation Of Apoptotic DNA Fragmentation DNA Damage Response, Detection Of DNA Damage Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Transcription Regulatory Region DNA Binding Protein Autoprocessing Cytoskeletal Anchoring At Plasma Membrane Regulation Of Centriole Replication Positive Regulation Of Gene Expression Positive Regulation Of SMAD Protein Import Into Nucleus Microvillus Assembly Microvillus Organization Negative Regulation Of Centrosome Duplication Microtubule Cytoskeleton Organization Regulation Of SMAD Protein Import Into Nucleus T Cell Apoptotic Process Filopodium Assembly Apoptotic DNA Fragmentation Macrophage Differentiation Cellular Response To Organic Substance Cellular Component Assembly Cellular Response To Superoxide Regulation Of Cellular Component Organization Response To Stimulus Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Execution Phase Of Apoptosis CENP-A Containing Nucleosome Assembly Response To Superoxide Protein ADP-ribosylation Response To Oxygen Radical Establishment Of Endothelial Barrier Negative Regulation Of Cellular Metabolic Process DNA Repair Ribosome Assembly Apoptotic Nuclear Changes Cellular Macromolecular Complex Assembly Histone Exchange Signal Transduction Involved In Regulation Of Gene Expression
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