GUCY1A3

Gene Name		guanylate cyclase 1, soluble, alpha 3
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Gene Ontology Annotations	Cellular Component	Guanylate Cyclase Complex, Soluble
	Molecular Function	Guanylate Cyclase Activity Receptor Activity GTP Binding Heme Binding
	Biological Process	CGMP Biosynthetic Process Nitric Oxide Mediated Signal Transduction Blood Coagulation Blood Circulation Regulation Of Blood Pressure Positive Regulation Of CGMP Biosynthetic Process Response To Defense-related Host Nitric Oxide Production Relaxation Of Vascular Smooth Muscle
Pathways		Platelet homeostasis Nitric oxide stimulates guanylate cyclase
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Coronary heart disease ( 22751097) Diastolic blood pressure ( 21909115) Systolic blood pressure ( 21909115)
Protein-protein Interactions		4 interactors: AGAP1 IKBKG MAPK8 STUB1
Entrez ID		2982
HPRD ID		00768
Ensembl ID		ENSG00000164116
Uniprot IDs		B3KU69 Q02108
PDB IDs		3UVJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Catalytic Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Protein Binding Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Negative Regulation Of Binding Regulation Of Catalytic Activity Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Signal Transduction Activation Of Innate Immune Response Regulation Of Protein Binding Regulation Of Signaling Positive Regulation Of Chaperone-mediated Protein Complex Assembly Positive Regulation Of Innate Immune Response Positive Regulation Of Metabolic Process MAPK Cascade Fc-epsilon Receptor Signaling Pathway Regulation Of Innate Immune Response Regulation Of Binding Fc Receptor Signaling Pathway JUN Phosphorylation Signal Transduction By Phosphorylation Positive Regulation Of Deacetylase Activity Cellular Response To Stress Ubiquitin-dependent SMAD Protein Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Determination Of Dorsal Identity Immune Response-regulating Cell Surface Receptor Signaling Pathway Intracellular Signal Transduction Regulation Of Glucocorticoid Metabolic Process Cellular Response To Nitric Oxide Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Signal Transduction Response To Nitric Oxide
Tagcloud ?		2j 6j buffer bxd coexpression congruent crosses dba distal extraordinary fluctuation gaba gabra1 gabra2 gabrb2 gabrb3 gabrg2 heritable massive naaa neurotransmission nos1 platforms remarkably subunits unlinked utrs zkscan1