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CD274
Gene Name
CD274 molecule
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Endomembrane System
Integral Component Of Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
T Cell Costimulation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of T Cell Proliferation
Regulation Of Activated T Cell Proliferation
Negative Regulation Of Activated T Cell Proliferation
Regulation Of T Cell Apoptotic Process
Toxin Transport
Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
Positive Regulation Of Interleukin-10 Secretion
Pathways
Costimulation by the CD28 family
PD-1 signaling
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
CD80
PDCD1
Entrez ID
29126
HPRD ID
05655
Ensembl ID
ENSG00000120217
Uniprot IDs
Q0GN75
Q2V8D5
Q9NZQ7
PDB IDs
3BIK
3BIS
3FN3
3SBW
Enriched GO Terms of Interacting Partners
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T Cell Costimulation
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Lymphocyte Activation
Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Regulation Of Cell Activation
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Regulation Of Cell Adhesion
Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of T-helper 1 Type Immune Response
Positive Regulation Of Alpha-beta T Cell Proliferation
Positive Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of T Cell Apoptotic Process
Positive Regulation Of Immune System Process
Positive Regulation Of Lymphocyte Apoptotic Process
Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of T-helper Cell Differentiation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of Leukocyte Apoptotic Process
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Regulation Of T-helper Cell Differentiation
Positive Regulation Of Interleukin-2 Production
Immune Response
Regulation Of Immune System Process
Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of Alpha-beta T Cell Differentiation
Regulation Of T Cell Apoptotic Process
Regulation Of Lymphocyte Apoptotic Process
Positive Regulation Of Cytokine Biosynthetic Process
Positive Regulation Of T Cell Proliferation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Lymphocyte Differentiation
Immune System Process
Regulation Of Cytokine Biosynthetic Process
Positive Regulation Of Lymphocyte Proliferation
Positive Regulation Of Mononuclear Cell Proliferation
Regulation Of T Cell Differentiation
Phosphatidylinositol-mediated Signaling
Regulation Of T Cell Proliferation
Positive Regulation Of Adaptive Immune Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Lymphocyte Differentiation
Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud
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9p24
actionable
arid1a
atlas
barr
bystander
cdkn2a
classifier
comes
comprises
cpg
ebv
enrollment
epstein
fail
gastrogenus
genomically
harbor
innocent
instability
intimately
l2
lytic
microsatellite
mlh1
msi
noncoding
pdcd1lg2
qualify