FFAR2

Gene Name		free fatty acid receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Projection
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding Lipid Binding
	Biological Process	Leukocyte Chemotaxis Involved In Inflammatory Response Mucosal Immune Response Regulation Of Acute Inflammatory Response Positive Regulation Of Cytokine Production Involved In Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus G-protein Coupled Receptor Signaling Pathway Lipid Storage Positive Regulation Of Chemokine Production Glucose Homeostasis Fat Cell Differentiation Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion Positive Regulation Of Interleukin-8 Secretion
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Free fatty acid receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CYB5R2 GNAO1 GNAQ IGF1R
Entrez ID		2867
HPRD ID		04824
Ensembl ID		ENSG00000126262
Uniprot IDs		C6KYL4 O15552
PDB IDs
Enriched GO Terms of Interacting Partners?		Dopamine Receptor Signaling Pathway Brain Development Head Development Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Inactivation Of MAPKK Activity G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuron Development Central Nervous System Development Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Generation Of Neurons Positive Regulation Of Steroid Hormone Biosynthetic Process Exocrine Pancreas Development Neurogenesis Phospholipase C-activating Dopamine Receptor Signaling Pathway Neuron Remodeling Negative Regulation Of Phosphorylation Positive Regulation Of Hormone Biosynthetic Process Cell Development Forebrain Development Regulation Of Melanocyte Differentiation Male Sex Determination Maternal Behavior Response To Vitamin E Insulin-like Growth Factor Receptor Signaling Pathway Nervous System Development Behavior Regulation Of Catenin Import Into Nucleus Regulation Of Catalytic Activity Regulation Of Developmental Pigmentation Phosphatidylinositol 3-kinase Signaling Sex Determination Regulation Of Hormone Biosynthetic Process Positive Regulation Of Steroid Metabolic Process Neuron Maturation Positive Regulation Of GTPase Activity Regulation Of Hormone Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Muscle Cell Apoptotic Process Forebrain Neuron Development Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Catalytic Activity Regulation Of GTPase Activity Positive Regulation Of Cytokinesis Regulation Of Kinase Activity Prostate Gland Epithelium Morphogenesis
Tagcloud ?		acetate alter autonomous believed coupling elevation encoded expect ffa2 ffa3 ffar3 gi glucose hyperglycemia inability indeed insufficient islets maintain obese pancreatic profound proper respond secretion stimulate summary tolerance worldwide