GNG11

Gene Name		guanine nucleotide binding protein (G protein), gamma 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane
	Molecular Function	GTPase Activity Signal Transducer Activity
	Biological Process	Energy Reserve Metabolic Process Signal Transduction G-protein Coupled Receptor Signaling Pathway Small Molecule Metabolic Process Cellular Response To Glucagon Stimulus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism G alpha (s) signalling events Glucagon-type ligand receptors Signal amplification Signaling by Wnt G beta:gamma signalling through PLC beta Metabolic disorders of biological oxidation enzymes G beta:gamma signalling through PI3Kgamma Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor G alpha (z) signalling events G alpha (12/13) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Class B/2 (Secretin family receptors) ADP signalling through P2Y purinoceptor 12 Glucagon signaling in metabolic regulation Prostacyclin signalling through prostacyclin receptor G-protein beta:gamma signalling Vasopressin regulates renal water homeostasis via Aquaporins Opioid Signalling Regulation of insulin secretion Activation of Kainate Receptors upon glutamate binding Aquaporin-mediated transport GPCR ligand binding beta-catenin independent WNT signaling Adrenaline,noradrenaline inhibits insulin secretion G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors GPCR downstream signaling Platelet homeostasis Ca2+ pathway G-protein activation Platelet activation, signaling and aggregation Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Heart rate ( 23583979)
Protein-protein Interactions		8 interactors: AMOTL2 CEP44 FOS GNB1 GNB4 MEOX2 SMURF1 ZHX1
Entrez ID		2791
HPRD ID		11979
Ensembl ID
Uniprot IDs		P61952 Q53Y01
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Glucagon Stimulus Response To Glucagon Cellular Response To Hormone Stimulus Skeletal Muscle Tissue Development Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Organ Development Tissue Development Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Response To Organonitrogen Compound Response To Transforming Growth Factor Beta Conditioned Taste Aversion Somite Specification Ubiquitin-dependent SMAD Protein Catabolic Process Cardiac Muscle Cell Apoptotic Process Response To Hormone Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Muscle Cell Apoptotic Process Muscle Organ Development Energy Derivation By Oxidation Of Organic Compounds Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Striated Muscle Tissue Development Cellular Response To Peptide Muscle Tissue Development Cellular Response To Prostaglandin E Stimulus Response To Light Stimulus G-protein Coupled Acetylcholine Receptor Signaling Pathway Sleep Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Response To Gravity Segment Specification Anatomical Structure Development Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E Protein Localization To Cell Surface Receptor Catabolic Process Generation Of Precursor Metabolites And Energy Organ Development Response To Immobilization Stress Response To Radiation Response To Peptide Hormone Signal Transduction Ectoderm Development Cell Surface Receptor Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Response To Organonitrogen Compound
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