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GNG4
Gene Name
guanine nucleotide binding protein (G protein), gamma 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Signal Transducer Activity
Protein Binding
Biological Process
Energy Reserve Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Negative Regulation Of Cell Growth
Small Molecule Metabolic Process
Cellular Response To Glucagon Stimulus
Pathways
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Glucagon-type ligand receptors
G beta:gamma signalling through PLC beta
Signaling by Wnt
Metabolic disorders of biological oxidation enzymes
G protein gated Potassium channels
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
Glucagon signaling in metabolic regulation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inwardly rectifying K+ channels
G-protein beta:gamma signalling
Opioid Signalling
Activation of Kainate Receptors upon glutamate binding
Aquaporin-mediated transport
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (q) signalling events
GPCR downstream signaling
Platelet homeostasis
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signal amplification
Potassium Channels
G beta:gamma signalling through PI3Kgamma
G alpha (12/13) signalling events
Class B/2 (Secretin family receptors)
Prostacyclin signalling through prostacyclin receptor
GABA B receptor activation
GABA receptor activation
Activation of G protein gated Potassium channels
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
GPCR ligand binding
beta-catenin independent WNT signaling
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Ca2+ pathway
G-protein activation
Drugs
Diseases
GWAS
Aging traits (
17903295
)
Protein-protein Interactions
8 interactors:
GNB1
GNB2
GNB3
GNB4
GNB5
RAF1
TFIP11
USHBP1
Entrez ID
2786
HPRD ID
11978
Ensembl ID
ENSG00000168243
Uniprot IDs
B1APZ0
P50150
PDB IDs
Enriched GO Terms of Interacting Partners
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Cellular Response To Glucagon Stimulus
Response To Glucagon
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Energy Reserve Metabolic Process
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Peptide
Cellular Response To Hormone Stimulus
Energy Derivation By Oxidation Of Organic Compounds
Response To Organonitrogen Compound
Response To Hormone
Generation Of Precursor Metabolites And Energy
Synaptic Transmission
Regulation Of Rhodopsin Mediated Signaling Pathway
Rhodopsin Mediated Signaling Pathway
Cellular Response To Organic Substance
Cell-cell Signaling
G-protein Coupled Receptor Signaling Pathway
Phototransduction, Visible Light
Response To Organic Substance
Detection Of Visible Light
Death-inducing Signaling Complex Assembly
Spliceosomal Complex Disassembly
Cellular Response To Light Stimulus
Phototransduction
Detection Of Light Stimulus
Oxidation-reduction Process
Cell Surface Receptor Signaling Pathway
Signal Transduction
Cellular Response To Radiation
Signaling
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Detection Of Abiotic Stimulus
Cell Communication
Platelet Activation
Negative Regulation Of Voltage-gated Calcium Channel Activity
Ras Protein Signal Transduction
Cardiac Muscle Cell Apoptotic Process
Muscle Cell Apoptotic Process
Cellular Response To Stimulus
Small Molecule Metabolic Process
Response To Abiotic Stimulus
Response To Hypoxia
Cellular Response To Prostaglandin E Stimulus
Response To Light Stimulus
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Cellular Response To Prostaglandin Stimulus
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