ERLEC1 and TSPYL6

		ERLEC1	TSPYL6
Description		endoplasmic reticulum lectin 1	TSPY like 6
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment	Chromatin Nucleus
	Molecular Function	Protein Binding Unfolded Protein Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Nucleosome Assembly
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		1 interacting genes: STK11	11 interacting genes: DVL3 KANK2 KRTAP13-2 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGEA6 MDFI RBPMS
Entrez ID		27248	388951
HPRD ID		10310	11652
Ensembl ID		ENSG00000068912	ENSG00000178021
Uniprot IDs		Q96DZ1 V9HWD3	A0A140VJY4 Q8N831
PDB IDs		8KES 8KET 8KEV
Enriched GO Terms of Interacting Partners?			Intermediate Filament
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