CNNM1

Description		cyclin and CBS domain divalent metal cation transport mediator 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Magnesium Ion Homeostasis Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 29403010 33339817) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 22412388) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
Novel Interacting Genes		1 novel interacting genes: CDK2
Interacting Genes		3 interacting genes: HSF2BP PTP4A1 PTP4A2
Entrez ID		26507
HPRD ID		07417
Ensembl ID		ENSG00000119946
Uniprot IDs		A0A8Q3SIV9 B4DKF7 B7Z5S3 Q9NRU3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chromatin Organization Y Chromosome Endosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity X Chromosome Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity Protection From Non-homologous End Joining At Telomere Female Meiosis I Regulation Of Heterochromatin Formation Early Endosome Double-strand Break Repair Involved In Meiotic Recombination DNA-templated Transcription Telomere Maintenance In Response To DNA Damage Mitotic G1/S Transition Checkpoint Signaling Cellular Response To Nitric Oxide Mitotic G1 DNA Damage Checkpoint Signaling Regulation Of DNA-templated DNA Replication Initiation Positive Regulation Of DNA-templated DNA Replication Cellular Response To Reactive Nitrogen Species Centrosome Duplication Female Meiotic Nuclear Division Response To Nitric Oxide DNA Repair Centriole Replication Regulation Of Chromatin Organization Male Meiosis I Cyclin-dependent Protein Serine/threonine Kinase Activity Centriole Assembly Cyclin Binding
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