GBP3

Description		guanylate binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Immune System Process Defense Response To Bacterium Innate Immune Response Defense Response To Virus Cytolysis In Another Organism Cellular Response To Lipopolysaccharide Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Pyroptotic Inflammatory Response
Pathways		Interferon gamma signaling CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity
Drugs
Diseases
GWAS		Carotid intima media thickness ( 26343869) Femur bone mineral density x serum urate levels interaction ( 34046847)
Novel Interacting Genes		1 novel interacting genes: LRRC8B
Interacting Genes		1 interacting genes: MAP4K4
Entrez ID		2635
HPRD ID		02683
Ensembl ID		ENSG00000117226
Uniprot IDs		Q9H0R5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ARF Protein Signal Transduction Positive Regulation Of Keratinocyte Migration Creatine Kinase Activity Positive Regulation Of Focal Adhesion Disassembly MAP Kinase Kinase Kinase Kinase Activity Volume-sensitive Anion Channel Activity Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane Cyclic Nucleotide Transport Guanine Nucleotide Transmembrane Transport Aspartate Transmembrane Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of Hippo Signaling C4-dicarboxylate Transport Nucleotide Transmembrane Transport Hippo Signaling Positive Regulation Of Focal Adhesion Assembly Purine-containing Compound Transmembrane Transport Purine Nucleotide Transport Adenine Nucleotide Transport Nucleotide Transport Negative Regulation Of Cell-matrix Adhesion Regulation Of Hippo Signaling Positive Regulation Of Epithelial Cell Migration Regulation Of Cell-substrate Junction Organization Positive Regulation Of Cell-matrix Adhesion Regulation Of Focal Adhesion Assembly Regulation Of Epithelial Cell Migration Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Small GTPase Mediated Signal Transduction Carbohydrate Derivative Transport Dicarboxylic Acid Transport Amino Acid Transmembrane Transport Positive Regulation Of Cell Junction Assembly Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Amino Acid Transport Organic Acid Transmembrane Transport Monoatomic Ion Channel Complex Carboxylic Acid Transmembrane Transport Monoatomic Anion Transmembrane Transport Monoatomic Anion Transport Organophosphate Ester Transport Regulation Of JNK Cascade Import Across Plasma Membrane
Tagcloud ?