GAPDHS

Description		glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor NADP Binding NAD Binding
	Biological Process	Glucose Metabolic Process Glycolytic Process Flagellated Sperm Motility Positive Regulation Of Glycolytic Process
Pathways		Association of TriC/CCT with target proteins during biosynthesis Glycolysis Gluconeogenesis
Drugs		NADH Zinc (+)-Rutamarin alcohol N-naphthalen-1-ylmethyl-2'-[3,5-dimethoxybenzamido]-2'-deoxy-adenosine 2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Diastolic blood pressure ( 28234671) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 28234671)
Novel Interacting Genes		1 novel interacting genes: CFLAR
Interacting Genes		4 interacting genes: ANXA1 APP SH3BP4 ZMYND19
Entrez ID		26330
HPRD ID		13566
Ensembl ID		ENSG00000105679
Uniprot IDs		A0A0K0K1K1 O14556
PDB IDs		3H9E 3PFW 5C7L 5C7O
Enriched GO Terms of Interacting Partners?		Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Apoptotic Process Cellular Response To Glucocorticoid Stimulus Response To Growth Factor Cellular Response To Growth Factor Stimulus Endocytosis Cellular Response To Corticosteroid Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Clathrin-coated Pit Positive Regulation Of Programmed Cell Death Positive Regulation Of Mitotic Cell Cycle Response To Glucocorticoid Regulation Of Interleukin-1 Production Regulation Of Cell Population Proliferation Myeloid Leukocyte Activation Import Into Cell Response To Corticosteroid Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Skeletal Myofibril Assembly Negative Regulation Of Myoblast Fusion Amino Acid Import Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Neutrophil Apoptotic Process Cytoplasmic Vesicle Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of T-helper 2 Cell Differentiation
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