FBXL3

Gene Name		F-box and leucine-rich repeat protein 3
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Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Circadian Rhythm Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CDC34 SKP1 UBE2D2
Entrez ID		26224
HPRD ID		05737
Ensembl ID		ENSG00000005812
Uniprot IDs		Q9UKT7
PDB IDs		4I6J
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Catabolic Process Positive Regulation Of Inclusion Body Assembly Negative Regulation Of CAMP-mediated Signaling Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Inclusion Body Assembly Mitotic Cell Cycle Process Cellular Protein Modification Process Histone Monoubiquitination Regulation Of CAMP-mediated Signaling Mitotic Cell Cycle SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia DNA Replication Initiation Histone Ubiquitination Protein Monoubiquitination Cell Cycle Process Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Neuron Apoptotic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Cell Cycle Positive Regulation Of Neuron Death Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		antigenic arising asxl1 bands casp5 cms colon colonic crebbp decay encode ep300 examples exon frameshift med8 microsatellite microsatellites msh3 msi neo nmd nonsense rgs12 sfrs12ip1 targetable termini transcripts ttk