FBXW2

Description		F-box and WD repeat domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Proteolysis Protein Modification Process
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 25673412)
Novel Interacting Genes		1 novel interacting genes: EXOSC2
Interacting Genes		12 interacting genes: BTRC CDC34 CDK2 CLVS2 CTNNB1 CUL1 MSX2 MYB RELA SKP1 TRIM54 UBE2D2
Entrez ID		26190
HPRD ID		09950
Ensembl ID		ENSG00000119402
Uniprot IDs		B4DT60 Q9UKT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Macromolecule Catabolic Process Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Protein Ubiquitination Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process SCF Ubiquitin Ligase Complex Lysosome Organization Ubiquitin Ligase Complex Scaffold Activity Proteasomal Protein Catabolic Process Catabolic Process Negative Regulation Of Protein Sumoylation Transcription Regulator Complex Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ubiquitin Ligase Activator Activity Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gliogenesis Nucleoplasm Cellular Response To Interleukin-6 Protein Modification Process Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of T Cell Receptor Signaling Pathway Response To Interleukin-6 Cytosol Branching Morphogenesis Of An Epithelial Tube Proteolysis Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Protein Sumoylation Response To Muscle Stretch Morphogenesis Of A Branching Epithelium Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Hindlimb Morphogenesis Morphogenesis Of A Branching Structure Embryonic Forelimb Morphogenesis Non-canonical NF-kappaB Signal Transduction Ubiquitin Conjugating Enzyme Activity Negative Regulation Of Metabolic Process
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