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GART
Gene Name
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Phosphoribosylamine-glycine Ligase Activity
Phosphoribosylformylglycinamidine Cyclo-ligase Activity
Phosphoribosylglycinamide Formyltransferase Activity
ATP Binding
Methyltransferase Activity
Metal Ion Binding
Biological Process
Brainstem Development
Purine Nucleobase Metabolic Process
'de Novo' IMP Biosynthetic Process
Glycine Metabolic Process
Purine Nucleobase Biosynthetic Process
Purine Ribonucleoside Monophosphate Biosynthetic Process
Response To Organic Substance
Response To Inorganic Substance
Cerebellum Development
Cerebral Cortex Development
Methylation
Small Molecule Metabolic Process
Tetrahydrofolate Biosynthetic Process
Nucleobase-containing Small Molecule Metabolic Process
Pathways
Purine ribonucleoside monophosphate biosynthesis
Purine metabolism
Metabolism of nucleotides
Drugs
Pemetrexed
Glycinamide Ribonucleotide
10-CF3C(OH)2-DDACTHF
Diseases
GWAS
Crohn's disease (
23128233
)
Protein-protein Interactions
2 interactors:
KPNA2
PXN
Entrez ID
2618
HPRD ID
00716
Ensembl ID
ENSG00000159131
Uniprot IDs
P22102
Q59HH3
PDB IDs
1MEJ
1MEN
1MEO
1NJS
1RBM
1RBQ
1RBY
1RBZ
1RC0
1RC1
1ZLX
1ZLY
2QK4
2V9Y
4EW1
4EW2
4EW3
Enriched GO Terms of Interacting Partners
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