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GART

Gene Name phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Image
Gene Ontology Annotations Cellular Component
  • Cytosol
  • Extracellular Vesicular Exosome
Molecular Function
  • Phosphoribosylamine-glycine Ligase Activity
  • Phosphoribosylformylglycinamidine Cyclo-ligase Activity
  • Phosphoribosylglycinamide Formyltransferase Activity
  • ATP Binding
  • Methyltransferase Activity
  • Metal Ion Binding
Biological Process
  • Brainstem Development
  • Purine Nucleobase Metabolic Process
  • 'de Novo' IMP Biosynthetic Process
  • Glycine Metabolic Process
  • Purine Nucleobase Biosynthetic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • Response To Organic Substance
  • Response To Inorganic Substance
  • Cerebellum Development
  • Cerebral Cortex Development
  • Methylation
  • Small Molecule Metabolic Process
  • Tetrahydrofolate Biosynthetic Process
  • Nucleobase-containing Small Molecule Metabolic Process
Pathways
  • Purine ribonucleoside monophosphate biosynthesis
  • Purine metabolism
  • Metabolism of nucleotides
Drugs
  • Pemetrexed
  • Glycinamide Ribonucleotide
  • 10-CF3C(OH)2-DDACTHF
Diseases
GWAS
  • Crohn's disease ( 23128233)
Protein-protein Interactions 2 interactors: KPNA2 PXN
Entrez ID 2618
HPRD ID 00716
Ensembl ID ENSG00000159131
Uniprot IDs P22102 Q59HH3
PDB IDs 1MEJ 1MEN 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0 1RC1 1ZLX 1ZLY 2QK4 2V9Y 4EW1 4EW2 4EW3
Enriched GO Terms of Interacting Partners?
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