EPC2

Gene Name		enhancer of polycomb homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Piccolo NuA4 Histone Acetyltransferase Complex
	Molecular Function
	Biological Process	DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 21123754) Protein quantitative trait loci ( 18464913)
Protein-protein Interactions		2 interactors: EED EZH2
Entrez ID		26122
HPRD ID		13274
Ensembl ID		ENSG00000135999
Uniprot IDs		Q52LR7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Histone Methylation Protein Methylation Regulation Of Gene Expression, Epigenetic Histone Modification Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Methylation Chromatin Modification G1 To G0 Transition Negative Regulation Of Epidermal Cell Differentiation Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation Chromatin Organization Protein Localization To Chromatin Regulation Of Histone H3-K27 Methylation Positive Regulation Of Protein Modification Process Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Striated Muscle Cell Differentiation Chromosome Organization Negative Regulation Of Transcription, DNA-templated Skeletal Muscle Tissue Regeneration Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Localization To Chromosome Positive Regulation Of Protein Metabolic Process Positive Regulation Of Epithelial To Mesenchymal Transition Genetic Imprinting Negative Regulation Of Epithelial Cell Differentiation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Histone Methylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Regulation Of Retinoic Acid Receptor Signaling Pathway Tissue Regeneration Regulation Of Histone Methylation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Cellular Response To Hydrogen Peroxide DNA Methylation Cerebellar Cortex Development Regulation Of Epidermis Development Positive Regulation Of Histone Modification Regulation Of Cellular Component Organization
Tagcloud ?		affymetrix altering barrett caudal cdx2 columnar emerges engineered epithelium gained homeobox htert immortalized intestinalization intestinalized intestine keratinocytes oesophageal oesophagus provoke remodelling rescued resemblance retroviral similarities transcriptase transiently unanswered unexpectedly