WSB1

Description		WD repeat and SOCS box containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Intracellular Signal Transduction Protein K27-linked Ubiquitination Protein Aggregate Center Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Chronic myeloid leukemia ( 21540461) Dental caries ( 23064961)
Interacting Genes		8 interacting genes: AXIN1 CSF3R DIO2 HIPK2 LRRK2 UBE2D2 UBE2D3 VHL
Entrez ID		26118
HPRD ID		15680
Ensembl ID		ENSG00000109046
Uniprot IDs		Q8NC76 Q9Y6I7
PDB IDs
Enriched GO Terms of Interacting Partners?		Catabolic Process Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin Conjugating Enzyme Activity Modification-dependent Protein Catabolic Process Negative Regulation Of DNA-templated Transcription, Elongation Protein Serine/threonine Kinase Binding Negative Regulation Of Transcription Elongation By RNA Polymerase II Wnt Signalosome Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Signal Transduction Anatomical Structure Morphogenesis Protein Polyubiquitination Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Cell Communication Negative Regulation Of Signaling SMAD Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Post-translational Protein Modification Granulocyte Colony-stimulating Factor Binding Protein Autoubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of BMP Signaling Pathway Beta-catenin Destruction Complex Assembly Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Protein Metabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Metabolic Process Macromolecule Catabolic Process Ubiquitin-like Ligase-substrate Adaptor Activity Regulation Of Transcription Elongation By RNA Polymerase II Canonical Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Axial Mesoderm Formation Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion
Tagcloud ?