HACL1

Gene Name		2-hydroxyacyl-CoA lyase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Peroxisome Peroxisomal Matrix
	Molecular Function	Magnesium Ion Binding Receptor Binding Carbon-carbon Lyase Activity Thiamine Pyrophosphate Binding Identical Protein Binding Cofactor Binding
	Biological Process	Fatty Acid Alpha-oxidation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Protein Oligomerization
Pathways		Alpha-oxidation of phytanate Metabolism of lipids and lipoproteins Peroxisomal lipid metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: MAGEB6 MAPK6 PEX5 ZMYND19
Entrez ID		26061
HPRD ID		09183
Ensembl ID		ENSG00000131373
Uniprot IDs		B3KPX4 Q9UJ83
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Negative Regulation Of Protein Oligomerization Protein Import Into Peroxisome Matrix Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Endoplasmic Reticulum Organization Fatty Acid Beta-oxidation Peroxisome Organization Positive Regulation Of Multicellular Organism Growth Intracellular Protein Transmembrane Transport Mitochondrial Membrane Organization Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cerebral Cortex Cell Migration Membrane Docking Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Forebrain Cell Migration
Tagcloud ?		athymic carboplatin cisplatin dms114 dms153 dms53 etoposide gls h128 h146 h187 h209 h526 h69 loc100129585 msi2 mts nu parp pkcs platinum potentiated potentiates potentiating sclc singly ubec2 veliparib xenografts