GALT

Description		galactose-1-phosphate uridylyltransferase
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	Protein Binding UDP-glucose:hexose-1-phosphate Uridylyltransferase Activity Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity Metal Ion Binding
	Biological Process	UDP-alpha-D-glucose Metabolic Process Galactose Metabolic Process Phosphate-containing Compound Metabolic Process Organophosphate Metabolic Process Galactose Catabolic Process Via UDP-galactose, Leloir Pathway Carbohydrate Derivative Metabolic Process
Pathways		Defective GALT can cause GALCT Galactose catabolism
Drugs
Diseases		Galactosemia
GWAS
Novel Interacting Genes		2 novel interacting genes: CCL19 CCL21
Interacting Genes		6 interacting genes: GRPEL1 KRTAP6-2 NQO1 TNK2 TRIP13 VAC14
Entrez ID		2592
HPRD ID		06106
Ensembl ID		ENSG00000213930
Uniprot IDs		A0A0S2Z3Y7 B2RAT6 P07902
PDB IDs		5IN3 6GQD
Enriched GO Terms of Interacting Partners?		Regulation Of Receptor-mediated Endocytosis CCR7 Chemokine Receptor Binding Regulation Of Dendritic Cell Dendrite Assembly Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Establishment Of T Cell Polarity Negative Regulation Of Dendritic Cell Apoptotic Process Regulation Of Endocytosis Chemokine Receptor Binding Immunological Synapse Formation Identical Protein Binding Dendritic Cell Chemotaxis Positive Regulation Of Glycoprotein Biosynthetic Process Cellular Response To Prostaglandin E Stimulus Eosinophil Chemotaxis Positive Regulation Of Glycoprotein Metabolic Process Cell Maturation Eosinophil Migration Regulation Of Antigen Processing And Presentation Dendritic Cell Migration Positive Regulation Of Neutrophil Chemotaxis Response To Prostaglandin E Positive Regulation Of Granulocyte Chemotaxis Cellular Response To Prostaglandin Stimulus CCR Chemokine Receptor Binding Regulation Of Vesicle-mediated Transport Positive Regulation Of Neutrophil Migration Developmental Maturation Regulation Of Neutrophil Chemotaxis Regulation Of Glycoprotein Biosynthetic Process Regulation Of Neutrophil Migration T Cell Costimulation Chemokine Activity Regulation Of Granulocyte Chemotaxis Positive Regulation Of Receptor-mediated Endocytosis Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Leukocyte Apoptotic Process Cell-cell Recognition Negative Regulation Of Sequestering Of Calcium Ion NADH Dehydrogenase (quinone) (non-electrogenic) Activity Positive Regulation Of Dendritic Cell Dendrite Assembly Dendritic Cell Dendrite Assembly Negative Regulation Of Dendritic Cell Dendrite Assembly PAS Complex Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Calcium Ion Transmembrane Import Into Cytosol Granulocyte Migration Establishment Of Cell Polarity Positive Regulation Of Leukocyte Chemotaxis
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