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PRDX5
Gene Name
peroxiredoxin 5
Image
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Peroxisome
Peroxisomal Matrix
Cytosol
Cytoplasmic Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
RNA Polymerase III Regulatory Region DNA Binding
Peroxidase Activity
Receptor Binding
Antioxidant Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Protein Dimerization Activity
Peroxiredoxin Activity
Peroxynitrite Reductase Activity
Biological Process
Response To Reactive Oxygen Species
Inflammatory Response
Response To Oxidative Stress
Negative Regulation Of Transcription From RNA Polymerase III Promoter
Positive Regulation Of Collagen Biosynthetic Process
Cellular Response To Reactive Oxygen Species
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Oxidoreductase Activity
Oxidation-reduction Process
Regulation Of Apoptosis Involved In Tissue Homeostasis
NADPH Oxidation
Reactive Nitrogen Species Metabolic Process
Pathways
Drugs
Auranofin
Diminazene
Benzoic Acid
Diseases
GWAS
Alopecia areata (
20596022
)
Crohn's disease (
21102463
)
Sarcoidosis (
22837380
)
Protein-protein Interactions
3 interactors:
APP
CCDC90B
PEX5
Entrez ID
25824
HPRD ID
05958
Ensembl ID
ENSG00000126432
Uniprot IDs
P30044
PDB IDs
1H4O
1HD2
1OC3
1URM
2VL2
2VL3
2VL9
3MNG
Enriched GO Terms of Interacting Partners
?
Regulation Of Multicellular Organism Growth
Neuromuscular Process
Regulation Of Developmental Growth
Negative Regulation Of Protein Homotetramerization
Synaptic Growth At Neuromuscular Junction
Protein Import Into Peroxisome Matrix, Translocation
Collateral Sprouting In Absence Of Injury
Protein Import Into Peroxisome Matrix, Docking
Forebrain Development
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Protein Homooligomerization
Axon Choice Point Recognition
Protein Import Into Peroxisome Membrane
Protein To Membrane Docking
Peroxisomal Membrane Transport
Regulation Of Growth
Neuron Remodeling
Negative Regulation Of Protein Oligomerization
Brain Development
Protein Import Into Peroxisome Matrix
Head Development
Cellular Copper Ion Homeostasis
Central Nervous System Development
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Establishment Of Protein Localization To Peroxisome
Protein Targeting To Peroxisome
Very Long-chain Fatty Acid Metabolic Process
Neuron Differentiation
Cerebral Cortex Neuron Differentiation
Regulation Of Protein Oligomerization
Neurological System Process
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Mating Behavior
Locomotion
Endoplasmic Reticulum Calcium Ion Homeostasis
Lipid Metabolic Process
RNA Polyadenylation
Neuron Recognition
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Endoplasmic Reticulum Organization
Fatty Acid Beta-oxidation
Peroxisome Organization
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tagcloud
?
accelerates
autoreactive
cba
draining
gpx2
gpx4
gpx7
h2
imbalances
immunoregulatory
iodide
isat
looked
microscopically
nai
peroxidases
peroxiredoxins
plausible
prdx1
prdx2
sat
thioredoxin
thyrocytes
thyroiditis
txn1
ucp2
ucp3
uncoupling
upregulates