FRK

Gene Name		fyn-related Src family tyrosine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding
	Biological Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cell Proliferation Cell Migration Actin Cytoskeleton Organization Cell Differentiation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 21665990) Cholesterol, total ( 20686565) LDL cholesterol ( 20686565) Urate levels ( 23263486)
Protein-protein Interactions		4 interactors: BNIP2 KHDRBS1 RB1 SF3B4
Entrez ID		2444
HPRD ID		05954
Ensembl ID
Uniprot IDs		P42685
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Cell Cycle Arrest Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Positive Regulation Of Metabolic Process Regulation Of Centromere Complex Assembly Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Striated Muscle Cell Differentiation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Cohesin Localization To Chromatin Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Gene Expression Muscle Cell Differentiation Positive Regulation Of Mitotic Metaphase/anaphase Transition Glial Cell Apoptotic Process Protein Localization To Chromosome, Centromeric Region Attachment Of Spindle Microtubules To Kinetochore MRNA Processing Positive Regulation Of Macrophage Differentiation Microtubule Cytoskeleton Organization Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Cycle Positive Regulation Of Translational Initiation Mitotic Sister Chromatid Cohesion Enucleate Erythrocyte Differentiation Positive Regulation Of Chromosome Segregation Muscle Structure Development Regulation Of Sister Chromatid Cohesion MRNA Metabolic Process Hepatocyte Apoptotic Process RNA Processing Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MRNA Splicing, Via Spliceosome Mitotic Metaphase Plate Congression Mitotic Cell Cycle Process Protein Localization To Chromosome Neuron Maturation Sister Chromatid Cohesion Metaphase Plate Congression Negative Regulation Of Smoothened Signaling Pathway Mitotic Cell Cycle Positive Regulation Of RNA Splicing Regulation Of Signal Transduction Microtubule-based Process Androgen Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Establishment Of Chromosome Localization
Tagcloud ?		accompanied accumulation alters arrest consequent disclosed distinctive e2f1 fyn g1 glioma hyperphosphorylated importantly inhibiting investigation member noteworthy nucleus prb proliferating proliferative promoted proper protective retinoblastoma sirna src suppressing suppressive