LY96

Gene Name		lymphocyte antigen 96
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Endosome Membrane Lipopolysaccharide Receptor Complex
	Molecular Function	Lipopolysaccharide Receptor Activity Protein Binding Coreceptor Activity
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Cellular Defense Response Cell Surface Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Detection Of Lipopolysaccharide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Innate Immune Response
Pathways		TRAF6 mediated induction of TAK1 complex TRIF-mediated TLR3/TLR4 signaling IKK complex recruitment mediated by RIP1 MyD88-independent cascade Toll Like Receptor TLR6:TLR2 Cascade Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon Toll Like Receptor 2 (TLR2) Cascade Toll Like Receptor TLR1:TLR2 Cascade Activated TLR4 signalling Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor 3 (TLR3) Cascade MyD88:Mal cascade initiated on plasma membrane TRIF-mediated programmed cell death Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CALM1 CDKN2C TLR2 TLR4
Entrez ID		23643
HPRD ID		05579
Ensembl ID		ENSG00000154589
Uniprot IDs		E5RJJ7 Q9Y6Y9
PDB IDs		1T2Z 2E56 2E59 2Z65 3FXI 3ULA 4G8A
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-17 Production Detection Of Molecule Of Bacterial Origin Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Lipoteichoic Acid Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process I-kappaB Phosphorylation Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Macrophage Cytokine Production Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Interferon-beta Production Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Nitric Oxide Metabolic Process Detection Of Biotic Stimulus Macrophage Activation Positive Regulation Of Interleukin-10 Production Reactive Nitrogen Species Metabolic Process Positive Regulation Of Interleukin-8 Production Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Response To Fungus Regulation Of Interferon-beta Production Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Nitric Oxide Biosynthetic Process Detection Of Chemical Stimulus Positive Regulation Of Chemokine Production Negative Regulation Of Phosphorylation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Interleukin-12 Production Regulation Of Intracellular Transport Positive Regulation Of Cytokine Production Involved In Immune Response Immune Response-regulating Signaling Pathway Regulation Of Chemokine Production Positive Regulation Of Tumor Necrosis Factor Production I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Toll-like Receptor 2 Signaling Pathway Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Detection Of Stimulus Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Type I Interferon Production Oligodendrocyte Differentiation Toll-like Receptor 4 Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Tagcloud ?		8v2 bad bead chips corrected ctla4 error false fdr genespring humanref hybridized il8 illumina inflation ingenuity institutes ipa mrs paxgene prove rankin recovery sdpr stroke tlr2 tlr4 tubes validation