CORO1C

Description		coronin 1C
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Endosome Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Flotillin Complex Sarcomere Lamellipodium Vesicle Ruffle Membrane Sarcolemma Cell Projection Synapse
	Molecular Function	Actin Binding Protein Binding Small GTPase Binding Actin Filament Binding
	Biological Process	Neural Crest Cell Migration Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Phagocytosis Actin Filament Organization Signal Transduction Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial Cell Migration Regulation Of Fibroblast Migration Endosomal Transport Ventricular System Development Corpus Callosum Development Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Establishment Of Protein Localization Positive Regulation Of Osteoclast Differentiation Macrophage Chemotaxis Negative Regulation Of Cellular Component Organization Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Membrane Fission Activation Of GTPase Activity Endosome Membrane Tubulation Endosome Fission Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Ruffle Assembly Positive Regulation Of Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Brain morphology (MOSTest) ( 32665545) Coronary artery disease and LDL cholesterol levels (multivariate analysis) ( 30525989) Heel bone mineral density x serum urate levels interaction ( 34046847) Hemoglobin ( 32888494) Immature fraction of reticulocytes ( 32888494) Low high density lipoprotein cholesterol levels ( 26879886) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		8 interacting genes: ANXA1 CEBPA ERCC6 LMO2 MMP14 RAC1 RSPH1 TIMP4
Entrez ID		23603
HPRD ID		09244
Ensembl ID		ENSG00000110880
Uniprot IDs		Q9ULV4
PDB IDs		7STY
Enriched GO Terms of Interacting Partners?		Response To Phenylpropanoid Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Immune System Process Regulation Of Cell Development Cellular Developmental Process Positive Regulation Of Cell Activation Regulation Of Leukocyte Migration Extracellular Matrix Phagocytic Cup Response To Hormone Focal Adhesion Cell Surface Receptor Signaling Pathway Actin Filament Regulation Of Hemopoiesis Positive Regulation Of Protein Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex Regulation Of Protein Metabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Regulation Of Cell-substrate Junction Organization Cellular Response To Genistein Regulation Of Focal Adhesion Assembly Negative Regulation Of GDF15-GFRAL Signaling Pathway Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Melanosome Lung Development Positive Regulation Of Metabolic Process Negative Regulation Of Hemopoiesis Positive Regulation Of Gene Expression Positive Regulation Of Endothelial Cell Migration Multicellular Organismal-level Homeostasis Notch Signaling Pathway CHOP-C/EBP Complex Response To Odorant Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis Radial Spoke Head 1 Radial Spoke Head 3 Regulation Of Cell-matrix Adhesion Inflammatory Response Response To Glucocorticoid
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