LEMD3

Gene Name		LEM domain containing 3
Image
Gene Ontology Annotations	Cellular Component	Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding DNA Binding Protein Binding
	Biological Process	Blood Vessel Endothelial Cell Migration Involved In Intussusceptive Angiogenesis Nucleus Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Activin Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Regulation Of Cell Cycle Regulation Of Extracellular Matrix Organization
Pathways		Mitotic Prophase Nuclear Envelope Breakdown Depolymerisation of the Nuclear Lamina Nuclear Envelope Reassembly Clearance of Nuclear Envelope Membranes from Chromatin Mitotic Anaphase Initiation of Nuclear Envelope Reformation Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: BCLAF1 SMAD1 SMAD2 SMAD9
Entrez ID		23592
HPRD ID		09704
Ensembl ID		ENSG00000174106
Uniprot IDs		Q9Y2U8
PDB IDs		2CH0
Enriched GO Terms of Interacting Partners?		Primary MiRNA Processing Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Kidney Epithelium Development SMAD Protein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Production Of MiRNAs Involved In Gene Silencing By MiRNA Kidney Development Renal System Development Positive Regulation Of Transcription, DNA-templated Gene Silencing By MiRNA Cellular Response To DsRNA Urogenital System Development Posttranscriptional Gene Silencing Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Silencing By RNA Skeletal System Development Cellular Response To Growth Factor Stimulus Response To DsRNA BMP Signaling Pathway Response To Growth Factor Mesoderm Formation Midbrain Development Embryonic Pattern Specification Mesoderm Morphogenesis Organ Growth Transcription, DNA-templated Tube Development RNA Biosynthetic Process Gene Silencing Positive Regulation Of Cellular Metabolic Process Formation Of Primary Germ Layer Positive Regulation Of Cell Differentiation Mesoderm Development Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Hindbrain Development Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry RNA Metabolic Process Gastrulation Epithelium Development
Tagcloud ?		12q13 12q14 3q14 3q15 atrial autism bands centres comprising delay deleted deletions ductus dysmorphism encompassing ended extends facial hmga2 microdeletions osteopoikilosis overlapping overlaps patent septal speech stature stenosis subtle