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FMO3

Description flavin containing dimethylaniline monoxygenase 3
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Monooxygenase Activity
  • N,N-dimethylaniline Monooxygenase Activity
  • Protein Binding
  • Oxidoreductase Activity
  • Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen
  • Trimethylamine Monooxygenase Activity
  • Albendazole Monooxygenase Activity
  • Hypotaurine Monooxygenase Activity
  • Flavin Adenine Dinucleotide Binding
  • NADP Binding
Biological Process
  • Taurine Biosynthetic Process
Pathways
  • FMO oxidises nucleophiles
  • Defective FMO3 causes TMAU
Drugs
Diseases
GWAS
  • Lentiform nucleus volume ( 22903471)
  • Serum metabolite levels ( 33031748)
Novel Interacting Genes 1 novel interacting genes: SERPINC1
Interacting Genes 4 interacting genes: CLEC10A CREB3 SACM1L SGSM3
Entrez ID 2328
HPRD ID 00633
Ensembl ID ENSG00000007933
Uniprot IDs A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Positive Regulation Of Deacetylase Activity
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© Madhavi K. Ganapathiraju 2012-2025