MTCL1

Description		microtubule crosslinking factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Extracellular Space Cytoplasm Cytoskeleton Spindle Microtubule Plasma Membrane Membrane Apical Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Midbody Microtubule Bundle
	Molecular Function	RNA Binding Protein Binding Microtubule Binding Protein Homodimerization Activity
	Biological Process	Microtubule Bundle Formation Chromosome Segregation Regulation Of Autophagy Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 28166215 30804561) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		7 interacting genes: C11orf68 CLK1 MARK2 RNF10 SRPK2 TUBA1B TUBB3
Entrez ID		23255
HPRD ID		11110
Ensembl ID		ENSG00000168502
Uniprot IDs		A0A8Q3SIW6 A0A8Q3WKN6 Q9Y4B5
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide Binding Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Protein Kinase Activity Microtubule Cytoskeleton Organization Structural Constituent Of Cytoskeleton Netrin Receptor Binding Kinase Activity Microtubule Bundle Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Nuclear Speck Organization Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Mitotic Cell Cycle Dorsal Root Ganglion Development Regulation Of RNA Splicing Regulation Of Neurofibrillary Tangle Assembly Transferase Activity Magnesium Ion Binding Microtubule-based Process R-loop Processing Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation Netrin-activated Signaling Pathway Microtubule Cytoskeleton
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