CUL9

Gene Name		cullin 9
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cullin-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding
	Biological Process	Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		6 interactors: PLXNB3 TP53 UBC UBE2E2 UBE2G2 UBE2L3
Entrez ID		23113
HPRD ID		06317
Ensembl ID		ENSG00000112659
Uniprot IDs		Q8IWT3
PDB IDs		2JUF
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Protein K48-linked Ubiquitination DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Cell Cycle Arrest Cellular Protein Catabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Mitotic DNA Integrity Checkpoint Cellular Response To Decreased Oxygen Levels Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Notch Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint
Tagcloud ?		abundance apaf cardiomyocytes conversely cyt cytochrome cytosolic damaged degradation e3 engaged glioma knocked ligase likewise mitochondrial mitochondrially myotubes neuroblastoma neurons parc parkin postmitotic proliferating proteasome released survive ubiquitination withstand