UNC13A

Description		unc-13 homolog A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Cell Projection Neuron Projection Terminal Bouton Synapse Presynaptic Active Zone
	Molecular Function	Calcium Ion Binding Calmodulin Binding Phospholipid Binding Zinc Ion Binding Syntaxin-1 Binding Diacylglycerol Binding Metal Ion Binding
	Biological Process	Exocytosis Chemical Synaptic Transmission Neurotransmitter Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Cell Differentiation Synaptic Transmission, Glutamatergic Regulation Of Synaptic Transmission, Glutamatergic Dense Core Granule Priming Neuronal Dense Core Vesicle Exocytosis Positive Regulation Of Dendrite Extension
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 19734901 22959728 24931836 27455348 29566793) Amyotrophic lateral sclerosis (sporadic) ( 24256812 28931804) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Benign prostatic hyperplasia ( 30988330) Frontotemporal dementia ( 24931836) IgG levels ( 28628107) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: EPB41L3 UBXN10
Entrez ID		23025
HPRD ID		19058
Ensembl ID		ENSG00000130477
Uniprot IDs		F8VZH8 Q9UPW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Paranode Region Of Axon Cytoskeletal Protein-membrane Anchor Activity Protein Localization To Juxtaparanode Region Of Axon Juxtaparanode Region Of Axon Paranode Region Of Axon Axolemma Protein Localization To Axon Cilium Paranodal Junction Assembly Myelin Maintenance Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Intraciliary Transport Particle B Cortical Actin Cytoskeleton Organization Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Cell Projection Organization Cortical Cytoskeleton Organization Cytoskeletal Protein Binding
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