UNC13A

Gene Name		unc-13 homolog A (C. elegans)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cell Junction Axon Neuromuscular Junction Presynaptic Membrane Neuron Projection Presynaptic Active Zone
	Molecular Function	Syntaxin-1 Binding Diacylglycerol Binding Metal Ion Binding Protein N-terminus Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Neurotransmitter Secretion Neuromuscular Junction Development Synaptic Vesicle Docking Synaptic Vesicle Maturation Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Regulation Of Short-term Neuronal Synaptic Plasticity Beta-amyloid Metabolic Process Regulation Of Synaptic Transmission, Glutamatergic Innervation
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728 19734901) Obesity-related traits ( 23251661)
Protein-protein Interactions		1 interactors: EPB41L3
Entrez ID		23025
HPRD ID		19058
Ensembl ID		ENSG00000130477
Uniprot IDs		Q9UPW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Paranode Region Of Axon Protein Localization To Juxtaparanode Region Of Axon Cytoskeletal Anchoring At Plasma Membrane Paranodal Junction Assembly Cortical Actin Cytoskeleton Organization Myelin Assembly Myelin Maintenance Cortical Cytoskeleton Organization Cell-cell Junction Assembly Myelination Maintenance Of Protein Location In Cell Protein Localization To Plasma Membrane Axon Ensheathment Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of Cell Shape Cell Junction Assembly Cell-cell Junction Organization Plasma Membrane Organization Protein Localization To Membrane
Tagcloud ?		19p13 8q24 9p21 allocating als amyotrophic c9orf72 causal conditioning conservative converging frontotemporal ftd hits identifies imputation inclusions meta neurotransmitter overlap proven replicated replicating shared sizes spg8 strumpellin tdp topmost