TPX2

Gene Name		TPX2, microtubule-associated
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Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Spindle Microtubule Microtubule Cytoskeleton Axon Hillock
	Molecular Function	Protein Binding ATP Binding GTP Binding Protein Kinase Binding
	Biological Process	Apoptotic Process Mitotic Nuclear Division Cell Proliferation Activation Of Protein Kinase Activity Cell Division Regulation Of Mitotic Spindle Organization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: AURKA CDK6 GOLGA2 HMMR NAP1L1 SIAH2 THAP11
Entrez ID		22974
HPRD ID		05802
Ensembl ID		ENSG00000088325
Uniprot IDs		Q643R0 Q96RR5 Q9ULW0
PDB IDs		1OL5 3E5A 3HA6
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Binding Negative Regulation Of Spindle Checkpoint Cell Dedifferentiation Cell Cycle Negative Regulation Of Binding Spindle Assembly Involved In Female Meiosis I Regulation Of Protein Binding Spindle Assembly Involved In Meiosis Mitotic Cell Cycle Spindle Stabilization Positive Regulation Of Oocyte Maturation Regulation Of Binding Mitotic Cell Cycle Phase Transition Meiotic Spindle Organization Cell Cycle Phase Transition Protein Localization To Centrosome Mitotic Centrosome Separation Negative Regulation Of Cellular Senescence Female Meiosis I Positive Regulation Of Oocyte Development Centrosome Separation Hematopoietic Stem Cell Differentiation Hyaluronan Catabolic Process Negative Regulation Of Cell Aging Dentate Gyrus Development Protein Localization To Cytoskeleton Histone-serine Phosphorylation Type B Pancreatic Cell Development
Tagcloud ?		actively autonomous clustering connected connectivity conserved degree displaying disseminated distant dormant enhances enriched etiology histologic identification inferred instead metastasis metastatic modules network networks proliferating tool transition utilized validate variation