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RPIA

Description ribose 5-phosphate isomerase A
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrion
  • Cytosol
Molecular Function
  • Ribose-5-phosphate Isomerase Activity
  • Protein Binding
  • Isomerase Activity
  • Carbohydrate Binding
  • Identical Protein Binding
  • Monosaccharide Binding
Biological Process
  • D-ribose Metabolic Process
  • Pentose-phosphate Shunt
  • Pentose-phosphate Shunt, Non-oxidative Branch
Pathways
  • RPIA deficiency: failed conversion of R5P to RU5P
  • RPIA deficiency: failed conversion of RU5P to R5P
  • Pentose phosphate pathway
Drugs
  • 4-phospho-L-threonic acid
Diseases
GWAS
  • Blood protein levels ( 30072576)
Novel Interacting Genes 1 novel interacting genes: PCDH7
Interacting Genes 20 interacting genes: ATPAF2 C14orf119 CENPP DDIT4L FOXP2 FXR1 FXR2 GORASP2 HSPB8 LNX1 NIF3L1 NTAQ1 PCMT1 PICK1 PTPN11 RNF208 SDCBP STK16 TXN2 VTA1
Entrez ID 22934
HPRD ID 01589
Ensembl ID ENSG00000153574
Uniprot IDs P49247
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
  • Positive Regulation Of Long-term Neuronal Synaptic Plasticity
  • Translation Regulator Activity
  • Dentate Gyrus Development
  • Regulation Of Long-term Neuronal Synaptic Plasticity
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© Madhavi K. Ganapathiraju 2012-2025