ANKRD6

Description		ankyrin repeat domain 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function
	Biological Process	Establishment Or Maintenance Of Cell Polarity Regulation Of Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 25827505) Coronary artery disease ( 29212778 33020668) Knee osteoarthritis ( 28916551) Metabolite levels (Pyroglutamine) ( 23934736) vWF and FVIII levels ( 21810271) Waist-hip ratio ( 28552196)
Interacting Genes		3 interacting genes: AXIN2 CSNK1E RIPK4
Entrez ID		22881
HPRD ID		09798
Ensembl ID		ENSG00000135299
Uniprot IDs		A0A384MEC3 A0AA34QVS0 B7Z3D2 Q9Y2G4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Canonical Wnt Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Wnt Signaling Pathway Regulation Of Mismatch Repair Regulation Of Wnt Signaling Pathway Intramembranous Ossification Regulation Of Centromeric Sister Chromatid Cohesion Regulation Of Chondrocyte Development Protein Serine Kinase Activity Maintenance Of DNA Repeat Elements Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Regulation Of Protein Catabolic Process Mitral Valve Morphogenesis Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Osteoblast Proliferation Secondary Heart Field Specification Beta-catenin Destruction Complex Heart Field Specification Negative Regulation Of Osteoblast Proliferation Protein Kinase Activity Dorsal/ventral Axis Specification Positive Regulation Of Non-canonical Wnt Signaling Pathway I-SMAD Binding Specification Of Animal Organ Identity Positive Regulation Of Catabolic Process Regulation Of Sister Chromatid Cohesion Positive Regulation Of Amyloid-beta Formation Atrioventricular Valve Morphogenesis Circadian Behavior Kinase Activity Rhythmic Behavior Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Amyloid Precursor Protein Catabolic Process DNA Metabolic Process Positive Regulation Of Amide Metabolic Process Cellular Response To Dexamethasone Stimulus Regulation Of Osteoblast Proliferation Aortic Valve Morphogenesis Positive Regulation Of Protein Metabolic Process
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