DOLK

Description		dolichol kinase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Dolichol Kinase Activity Protein Binding Kinase Activity Transferase Activity
	Biological Process	Protein N-linked Glycosylation Dolichyl Diphosphate Biosynthetic Process Lipid Metabolic Process Dolichyl Monophosphate Biosynthetic Process Dolichol Phosphate Mannose Biosynthetic Process
Pathways		Synthesis of dolichyl-phosphate Defective DOLK causes DOLK-CDG
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS
Interacting Genes		21 interacting genes: APPBP2 CD79A CHODL CREB3 CREB3L1 EDA FAM209A FNDC9 GALNT8 GJA8 GPX8 KCNA1 KCNA10 KCNA3 KCNA6 SLC7A6 SYNPR TMEM45B TMEM80 UBQLN1 VSIR
Entrez ID		22845
HPRD ID		15525
Ensembl ID		ENSG00000175283
Uniprot IDs		A0A0S2Z597 Q9UPQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Delayed Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Regulation Of Response To Endoplasmic Reticulum Stress Protein Complex Oligomerization Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway L-lysine:L-arginine Antiporter Activity Positive Regulation Of Deacetylase Activity Negative Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Collagen Catabolic Process Regulation Of Collagen Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway
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