FCN2

Gene Name		ficolin (collagen/fibrinogen domain containing lectin) 2
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Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Antigen Binding Protein Binding Proteoglycan Binding Calcium-dependent Protein Binding Mannan Binding
	Biological Process	Complement Activation, Lectin Pathway Complement Activation Opsonization Recognition Of Apoptotic Cell Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Creation of C4 and C2 activators Complement cascade Ficolins bind to repetitive carbohydrate structures on the target cell surface Initial triggering of complement Lectin pathway of complement activation Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MASP1 MASP2
Entrez ID		2220
HPRD ID		03376
Ensembl ID		ENSG00000160339
Uniprot IDs		Q15485
PDB IDs		2J0G 2J0H 2J0Y 2J1G 2J2P 2J3F 2J3G 2J3O 2J3U 2J61
Enriched GO Terms of Interacting Partners?		Complement Activation, Lectin Pathway Complement Activation Protein Activation Cascade Humoral Immune Response Positive Regulation Of Immune Response Innate Immune Response Regulation Of Immune Response Negative Regulation Of Complement Activation Positive Regulation Of Immune System Process Regulation Of Complement Activation Immune Response Regulation Of Immune System Process Defense Response Proteolysis Regulation Of Humoral Immune Response Regulation Of Acute Inflammatory Response Immune System Process Complement Activation, Classical Pathway Negative Regulation Of Immune Response Humoral Immune Response Mediated By Circulating Immunoglobulin Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Response To Stress Leukocyte Mediated Immunity Adaptive Immune Response Regulation Of Inflammatory Response Receptor-mediated Endocytosis Negative Regulation Of Protein Processing Negative Regulation Of Immune System Process Regulation Of Protein Processing
Tagcloud ?		algorithm carcinoma centralities cluster communicating constructed cxcl14 esr1 experiment genome helped hepatitis hepatocellular holding network networks nodes obtain relevance rfx5 selected significance sub ten top understand value virus wide