ACSL4

Gene Name		acyl-CoA synthetase long-chain family member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Membrane Lipid Particle Membrane Integral Component Of Membrane Neuronal Cell Body ER-mitochondrion Membrane Contact Site Extracellular Vesicular Exosome
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Response To Nutrient Lipid Biosynthetic Process Fatty Acid Transport Triglyceride Biosynthetic Process Positive Regulation Of Cell Growth Negative Regulation Of Prostaglandin Secretion Long-chain Fatty-acyl-CoA Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Embryonic Process Involved In Female Pregnancy Dendritic Spine Development Response To Interleukin-15
Pathways		Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs		Icosapent Troglitazone Rosiglitazone
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP DSE YWHAQ
Entrez ID		2182
HPRD ID		02152
Ensembl ID		ENSG00000068366
Uniprot IDs		O60488 Q5JWV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Dermatan Sulfate Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Cellular Copper Ion Homeostasis Chondroitin Sulfate Biosynthetic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Brain Development Chondroitin Sulfate Proteoglycan Biosynthetic Process Head Development Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Heparan Sulfate Proteoglycan Metabolic Process RNA Polyadenylation Neuron Recognition Substantia Nigra Development Apoptotic Process Central Nervous System Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Programmed Cell Death Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Neural Nucleus Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Proteoglycan Biosynthetic Process Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitochondrion Organization Chondroitin Sulfate Metabolic Process
Tagcloud ?		acyl anchorage androgen biomarker coa consequences databases dependence etoposide forced hormone lapatinib mcf mediator monitored nude public qnbc quadruple referred simultaneous skbr3 steroid stimulatory synthetase tamoxifen tnbc triacsin utilized