AK1

Gene Name		adenylate kinase 1
Image
Gene Ontology Annotations	Cellular Component	Outer Dense Fiber Cytoplasm Cytosol Plasma Membrane Sperm Flagellum Extracellular Vesicular Exosome
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process Cell Cycle Arrest Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process AMP Metabolic Process ATP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs		Bis(Adenosine)-5\'-Pentaphosphate
Diseases
GWAS
Protein-protein Interactions		6 interactors: APP FHL2 TERF1 TERF2IP TINF2 TRIM63
Entrez ID		203
HPRD ID		00046
Ensembl ID		ENSG00000106992
Uniprot IDs		P00568 Q5T9B7 Q6FGX9
PDB IDs		1Z83 2C95
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase RNA-dependent DNA Replication Regulation Of Chromosome Organization Protein Localization To Chromosome Negative Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Replication Homeostatic Process Negative Regulation Of Protein ADP-ribosylation Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of Protein ADP-ribosylation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Atrial Cardiac Muscle Cell Development Negative Regulation Of Cellular Protein Metabolic Process Telomere Maintenance Via Telomere Shortening Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Negative Regulation Of Protein Glycosylation Negative Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Organelle Organization Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Skeletal Muscle Atrophy Chromosome Organization DNA Metabolic Process Axon Choice Point Recognition Striated Muscle Atrophy Telomere Assembly
Tagcloud ?		aids biosynthesis cdk5r2 cycles deepen drugable ephb2 figure hek293t hiv host kinases library ltr nfkappab overlapped p38mapk plasmid prkacb regimens repress rnai shrna silenced stably therapeutics throughput uncovers vital