PIKFYVE

Gene Name		phosphoinositide kinase, FYVE finger containing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytosol Cell-cell Junction Endosome Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity Metal Ion Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Receptor-mediated Endocytosis Myelin Assembly Protein Localization To Nucleus Intracellular Signal Transduction Phosphatidylinositol-3-phosphate Biosynthetic Process Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways		Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Phospholipid metabolism Synthesis of PIPs at the late endosome membrane PI Metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP RABEPK VAC14
Entrez ID		200576
HPRD ID		17852
Ensembl ID		ENSG00000115020
Uniprot IDs		Q9Y2I7
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Secretion By Cell
Tagcloud ?		accordingly amp ampk atpase carriers channels creatine depleted downregulates ensures exchanger gap glycogen gsk3beta gtpase junctional labels membane monocarboxylate na osmolyte profoundly pumps rab sensing stabilizes tbc1d1 tensin transporters