AIF1

Gene Name		allograft inflammatory factor 1
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Gene Ontology Annotations	Cellular Component	Phagocytic Cup Nucleus Cytoplasm Cytosol Actin Filament Lamellipodium Ruffle Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Calcium Ion Binding Actin Filament Binding
	Biological Process	Microglial Cell Activation Positive Regulation Of Protein Phosphorylation Phagocytosis, Engulfment Inflammatory Response Negative Regulation Of Gene Expression Positive Regulation Of Muscle Hyperplasia Rac Protein Signal Transduction Actin Filament Polymerization Cellular Response To Extracellular Stimulus Cellular Response To Hormone Stimulus Positive Regulation Of T Cell Proliferation Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Actin Filament Bundle Assembly Response To Electrical Stimulus Cellular Response To Morphine Cellular Response To Interferon-gamma Cellular Response To Hydroperoxide Negative Regulation Of Smooth Muscle Cell Chemotaxis Positive Regulation Of Smooth Muscle Cell Chemotaxis Positive Regulation Of Monocyte Chemotaxis Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of T Cell Migration
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 22936669) Height ( 23563607) Neonatal lupus ( 20662065) Weight ( 19079260)
Protein-protein Interactions		2 interactors: ACTA1 LCP1
Entrez ID		199
HPRD ID		03496
Ensembl ID		ENSG00000204472
Uniprot IDs		I3WTX1 P55008 Q4V347
PDB IDs		2D58 2G2B
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Fiber Adaptation Actin Filament Organization Protein Kinase A Signaling Skeletal Muscle Thin Filament Assembly Actin Cytoskeleton Organization Skeletal Myofibril Assembly Skeletal Muscle Adaptation Actin Filament-based Process Skeletal Muscle Fiber Development Cytoskeleton Organization Myotube Cell Development Response To Lithium Ion Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Movement Of Cell Or Subcellular Component Muscle Fiber Development Myotube Differentiation Actin Filament-based Movement Actin Filament Bundle Assembly T Cell Activation Involved In Immune Response Organ Regeneration Cellular Component Assembly Myofibril Assembly Actomyosin Structure Organization Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Cell Growth Leukocyte Activation Involved In Immune Response Striated Muscle Cell Development Muscle Cell Development Organ Development Organelle Organization Response To Mechanical Stimulus Muscle Contraction Striated Muscle Cell Differentiation Regulation Of Intracellular Protein Transport Muscle System Process Muscle Organ Development T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Striated Muscle Tissue Development Leukocyte Cell-cell Adhesion Muscle Cell Differentiation Response To Metal Ion Homotypic Cell-cell Adhesion Muscle Tissue Development
Tagcloud ?		3xmyc assigned athanogene bag6 bcl2 bioinformatics classes elucidating highlighted immunoprecipitated infectious insertion interactome interested involve kegg lc locations marc nonstructural nsp2 ontology porcine prrsv replication reproductive subcellular tag transporting