CFD

Gene Name		complement factor D (adipsin)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Platelet Degranulation Proteolysis Complement Activation Complement Activation, Alternative Pathway Blood Coagulation Platelet Activation Innate Immune Response
Pathways		Alternative complement activation Complement cascade Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Initial triggering of complement Innate Immune System
Drugs		Isatoic Anhydride 3,4-Dichloroisocoumarin
Diseases
GWAS
Protein-protein Interactions		2 interactors: HDHD2 SERPINF2
Entrez ID		1675
HPRD ID		00600
Ensembl ID
Uniprot IDs		P00746
PDB IDs		1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWA 2XWB 4D9R
Enriched GO Terms of Interacting Partners?		Regulation Of Blood Vessel Size By Renin-angiotensin Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Plasminogen Activation Negative Regulation Of Fibrinolysis Regulation Of Fibrinolysis Positive Regulation Of Transforming Growth Factor Beta Production Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Metabolic Process Fibrinolysis Positive Regulation Of Blood Coagulation Regulation Of Collagen Metabolic Process Acute-phase Response Positive Regulation Of Coagulation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Wound Healing Positive Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Blood Coagulation Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Coagulation Collagen Fibril Organization Regulation Of Stress Fiber Assembly Negative Regulation Of Wound Healing Platelet Degranulation Regulation Of Blood Vessel Size Regulation Of Tube Size Acute Inflammatory Response Regulation Of Systemic Arterial Blood Pressure Renal System Process Regulation Of Blood Coagulation Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of JNK Cascade Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Wound Healing Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Blood Pressure Regulation Of Stress-activated MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Platelet Activation Positive Regulation Of Cytoskeleton Organization
Tagcloud ?		293t adjust bypassing compact concatenated constrictions cutting deal deploy deterministic device devices fabricated flowing geometric hek hydrodynamic immobilization inherent mathematical microfluidic path pdms saving serpentine tens thousands trapping works