DGKQ

Gene Name		diacylglycerol kinase, theta 110kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Nuclear Speck
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Binding Activating Transcription Factor Binding Phospholipase Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter G-protein Coupled Receptor Signaling Pathway Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Phosphorylation CAMP-mediated Signaling Platelet Activation Response To ATP Thrombin Receptor Signaling Pathway Protein Kinase C Signaling
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		Parkinson's disease ( 22451204 22438815 20070850) Parkinson's disease (familial) ( 18985386)
Protein-protein Interactions		1 interactors: RHOA
Entrez ID		1609
HPRD ID		03127
Ensembl ID		ENSG00000145214
Uniprot IDs		P52824 Q59FF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Migration Apolipoprotein A-I-mediated Signaling Pathway Cleavage Furrow Formation Ossification Involved In Bone Maturation Bone Maturation Negative Chemotaxis Mitotic Spindle Assembly Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Osteoblast Proliferation Substantia Nigra Development Wound Healing, Spreading Of Cells Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Mitotic Spindle Organization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Trabecula Morphogenesis Neural Nucleus Development Regulation Of Cytokinesis Rho Protein Signal Transduction Morphogenesis Of An Epithelial Sheet Negative Regulation Of Axonogenesis Regulation Of Stress Fiber Assembly Apical Junction Assembly Positive Regulation Of Axonogenesis Spindle Assembly Midbrain Development Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Ephrin Receptor Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Cytokinesis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development Spindle Organization Positive Regulation Of Cell Division Phosphatidylinositol-mediated Signaling Negative Regulation Of Cell Projection Organization Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Axonogenesis Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Protein Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta
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