CTSV

Description		cathepsin V
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Lysosomal Lumen
	Molecular Function	Cysteine-type Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Extracellular Matrix Disassembly Proteolysis Involved In Protein Catabolic Process
Pathways		Endosomal/Vacuolar pathway Degradation of the extracellular matrix Activation of Matrix Metalloproteinases Trafficking and processing of endosomal TLR Assembly of collagen fibrils and other multimeric structures MHC class II antigen presentation RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs		3-amino-5-phenylpentane 4-Methylpiperazin-1-Yl Carbonyl Group
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: KCNJ1
Interacting Genes		13 interacting genes: APC BMPR1A BRAF BUB1 CDKN2A CTNNA1 DCC DLC1 MLH1 MLH3 PDGFRL RB1 SRC
Entrez ID		1515
HPRD ID		04495
Ensembl ID		ENSG00000136943
Uniprot IDs		B2R717 O60911
PDB IDs		1FH0 3H6S 3KFQ 7PK4 7Q8D 7Q8F 7Q8G 7Q8H 7Q8I 7Q8J 7Q8K 7Q8L 7Q8M 7Q8N 7Q8O 7Q8P 7Q8Q 7Q9H 7QFF 7QFH 7QGW 7QHJ 7QHK 7QNS 7QO2
Enriched GO Terms of Interacting Partners?		Chiasma Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Anatomical Structure Morphogenesis Negative Regulation Of Nervous System Development Negative Regulation Of Cell Development Negative Regulation Of Neurogenesis Negative Regulation Of Cell-matrix Adhesion Mismatch Repair Complex Regulation Of Neurogenesis Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Cellular Component Organization Negative Regulation Of Kinase Activity Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Signal Transduction Negative Regulation Of Chromosome Organization Regulation Of Phosphorylation Intracellular Signal Transduction Regulation Of Mitotic Sister Chromatid Separation Gamma-catenin Binding Regulation Of Chromosome Organization Regulation Of Chromosome Separation Negative Regulation Of Protein Kinase Activity Regulation Of Cell Development Animal Organ Morphogenesis Somatic Stem Cell Population Maintenance Caveola Regulation Of Nervous System Development Apoptotic Process Regulation Of Cell-substrate Adhesion Negative Regulation Of Cell-substrate Adhesion Mismatched DNA Binding Regulation Of Kinase Activity ATP Binding Cell Junction Assembly Regulation Of Mitotic Metaphase/anaphase Transition Programmed Cell Death Cell Death Regulation Of Phosphorus Metabolic Process Odontogenesis Ruffle Membrane Negative Regulation Of Protein Phosphorylation Regulation Of Sister Chromatid Segregation Regulation Of Cell Motility ATP-dependent DNA Damage Sensor Activity Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Multicellular Organismal Process
Tagcloud ?