CTSH

Gene Name		cathepsin H
Image
Gene Ontology Annotations	Cellular Component	Outer Dense Fiber Acrosomal Vesicle Extracellular Space Lysosome Cytosol Extracellular Vesicular Exosome Alveolar Lamellar Body
	Molecular Function	Endopeptidase Activity Aminopeptidase Activity Cysteine-type Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process HLA-A Specific Activating MHC Class I Receptor Activity Kininogen Binding Protein Complex Binding Protein Self-association Thyroid Hormone Binding
	Biological Process	Metanephros Development T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response-regulating Signaling Pathway Proteolysis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Spermatogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Neuropeptide Catabolic Process Bradykinin Catabolic Process Positive Regulation Of Peptidase Activity Antigen Processing And Presentation Positive Regulation Of Cell Migration Zymogen Activation Protein Destabilization Response To Retinoic Acid Membrane Protein Proteolysis Negative Regulation Of Apoptotic Process Surfactant Homeostasis Positive Regulation Of Angiogenesis Dichotomous Subdivision Of Terminal Units Involved In Lung Branching ERK1 And ERK2 Cascade Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Apoptotic Signaling Pathway
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265) Type 1 diabetes ( 19430480 18978792)
Protein-protein Interactions		5 interactors: BGLAP CSTA CSTB SFTPB XRN1
Entrez ID		1512
HPRD ID		00288
Ensembl ID
Uniprot IDs		P09668
PDB IDs		1BZN
Enriched GO Terms of Interacting Partners?		Response To Vitamin K Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Nuclear MRNA Surveillance Response To Hydroxyisoflavone RNA Surveillance Histone MRNA Catabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing RRNA Catabolic Process Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Response To Gravity Cellular Response To Vitamin D Histone MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Osteoblast Development Response To Vitamin D Regulation Of Proteolysis Regulation Of Bone Resorption Response To Testosterone Cellular Response To Nutrient Regulation Of Bone Remodeling Peptide Cross-linking Negative Regulation Of Catalytic Activity Response To Zinc Ion Bone Mineralization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Cellular Protein Metabolic Process Response To Activity Respiratory Gaseous Exchange
Tagcloud ?		17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 tnfsf13b tnfsf25 vsv