CCBE1

Description		collagen and calcium binding EGF domains 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Extracellular Matrix
	Molecular Function	Protease Binding Calcium Ion Binding Protein Binding Collagen Binding
	Biological Process	Angiogenesis Lymph Vessel Development Lymphangiogenesis Sprouting Angiogenesis Respiratory System Process Respiratory Gaseous Exchange By Respiratory System Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Processing Lung Development Endothelial Cell Migration Positive Regulation Of Angiogenesis Venous Blood Vessel Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Lymphangiogenesis Lymphatic Endothelial Cell Migration
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Appendicular lean mass ( 33097823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23857890) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) PR interval ( 32439900) Pre-treatment viral load in HIV-1 infection ( 31219150) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia x sex interaction ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189)
Interacting Genes		12 interacting genes: CEP55 COPS6 FBXO7 FXR1 INCA1 KLHL12 KRT27 KRT36 LNX1 SIAH2 STX11 TOX4
Entrez ID		147372
HPRD ID		08703
Ensembl ID		ENSG00000183287
Uniprot IDs		A0A8Q3WKU1 Q6UXH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Structural Constituent Of Skin Epidermis Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Proteolysis Involved In Protein Catabolic Process Intermediate Filament Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Signaling Pathway Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Nucleus Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Ubiquitin-like Ligase-substrate Adaptor Activity Lewy Body Core
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