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CST3
Gene Name
cystatin C
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Vesicular Exosome
Molecular Function
Beta-amyloid Binding
Protease Binding
Endopeptidase Inhibitor Activity
Cysteine-type Endopeptidase Inhibitor Activity
Protein Binding
Biological Process
Defense Response
Negative Regulation Of Peptidase Activity
Negative Regulation Of Collagen Catabolic Process
Negative Regulation Of Extracellular Matrix Disassembly
Negative Regulation Of Endopeptidase Activity
Regulation Of Tissue Remodeling
Extracellular Fibril Organization
Negative Regulation Of Proteolysis
Negative Regulation Of Elastin Catabolic Process
Negative Regulation Of Blood Vessel Remodeling
Pathways
Amyloids
Drugs
Diseases
GWAS
Chronic kidney disease (
20383146
)
Cystatin C (
17903292
)
Protein-protein Interactions
9 interactors:
ATXN1
C4A
CSTB
CTSB
CTSD
CTSL
CTSS
PDZD2
RNF115
Entrez ID
1471
HPRD ID
05056
Ensembl ID
ENSG00000101439
Uniprot IDs
P01034
PDB IDs
1G96
1R4C
1TIJ
3GAX
3NX0
3PS8
3QRD
3S67
3SVA
Enriched GO Terms of Interacting Partners
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Cellular Response To Thyroid Hormone Stimulus
Collagen Catabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Response To Thyroid Hormone
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Extracellular Matrix Organization
Extracellular Structure Organization
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Positive Regulation Of Innate Immune Response
Protein Catabolic Process
Positive Regulation Of Immune Response
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Innate Immune Response
Proteolysis
Adaptive Immune Response
Antigen Processing And Presentation
Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Catabolic Process
Immune System Process
Immune Response-regulating Signaling Pathway
Basement Membrane Disassembly
Macrophage Apoptotic Process
Adult Locomotory Behavior
Immune Response
Regulation Of Immune System Process
Defense Response
Cellular Response To Hormone Stimulus
Adult Behavior
Myeloid Cell Apoptotic Process
Positive Regulation Of Apoptotic Cell Clearance
Inflammatory Cell Apoptotic Process
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Locomotory Behavior
Regulation Of Apoptotic Cell Clearance
Negative Regulation Of Endopeptidase Activity
Response To Hormone
Negative Regulation Of Peptidase Activity
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