ADRA1B

Description		adrenoceptor alpha 1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Caveola Membrane Nuclear Membrane
	Molecular Function	G Protein-coupled Receptor Activity Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Regulation Of Vasoconstriction Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of Cardiac Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Neuron-glial Cell Signaling
Pathways		Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs		Amphetamine Midodrine Ranolazine Ziprasidone Cabergoline Ropinirole Dapiprazole Dihydroergotamine Amitriptyline Olanzapine Alfuzosin Alfuzosin Clozapine Norepinephrine Mirtazapine Phenylephrine Loxapine Prochlorperazine Prazosin Prazosin Imipramine Chlorpromazine Chlorpromazine Buspirone Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Thioridazine Phentolamine Ergotamine Tizanidine Tamsulosin Paroxetine Methoxamine Trimipramine Risperidone Modafinil Fenoldopam Dobutamine Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Promethazine Carvedilol Carvedilol Doxepin Nefazodone Desipramine Terazosin Escitalopram Pergolide Bromocriptine Quetiapine Aripiprazole Paliperidone Mephentermine Methotrimeprazine Dextroamphetamine Dextroamphetamine Phendimetrazine Periciazine Acepromazine Thioproperazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Pizotifen Silodosin Ocaperidone Droxidopa Xylometazoline Tetryzoline Perospirone Brexpiprazole Dosulepin Viloxazine Etoperidone Lorpiprazole Cirazoline Synephrine Arotinolol Moxisylyte Aranidipine Pipamperone Racepinephrine Dihydroergocornine DL-Methylephedrine Indigotindisulfonic acid Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Diastolic blood pressure ( 27841878) Plasma anti-thyroglobulin levels ( 29678681) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		11 interacting genes: ADRA1A AP2M1 EZR FLNC GNA11 GNAQ NOS1 PPP1R9B PRKCA SAG STAT1
Entrez ID		147
HPRD ID		00080
Ensembl ID		ENSG00000170214
Uniprot IDs		P35368
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Hormone Phototransduction System Process Receptor Internalization G Protein-coupled Receptor Binding Phospholipase C-activating Serotonin Receptor Signaling Pathway Detection Of Light Stimulus Photoreceptor Outer Segment Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Biological Quality Phototransduction, Visible Light Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Protein Localization To Plasma Membrane Guanyl Nucleotide Binding Detection Of Abiotic Stimulus G Protein-coupled Receptor Signaling Pathway Transmembrane Transporter Binding Positive Regulation Of Transport G Protein-coupled Acetylcholine Receptor Signaling Pathway G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Filopodium Assembly Signal Transduction Regulation Of The Force Of Heart Contraction Regulation Of Protein Localization To Cell Periphery Disordered Domain Specific Binding Positive Regulation Of Protein Localization Detection Of Visible Light Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To PH Response To Prostaglandin E Entrainment Of Circadian Clock Enzyme Regulator Activity Regulation Of Protein Localization Regulation Of Blood Pressure Regulation Of Protein Localization To Membrane Receptor-mediated Endocytosis Plasma Membrane Heterotrimeric G-protein Complex Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cellular Localization Actin Filament Binding Response To PH Blood Circulation Response To Ketone Acetylcholine Receptor Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway
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