DUSP19

Gene Name		dual specificity phosphatase 19
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Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Kinase Inhibitor Activity MAP-kinase Scaffold Activity Protein Tyrosine/threonine Phosphatase Activity JUN Kinase Phosphatase Activity Protein Kinase Activator Activity Mitogen-activated Protein Kinase Kinase Kinase Binding
	Biological Process	Inactivation Of MAPK Activity Negative Regulation Of Protein Kinase Activity Protein Dephosphorylation JNK Cascade Peptidyl-tyrosine Dephosphorylation Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JUN Kinase Activity Positive Regulation Of Protein Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ALAS1 MAP2K7 MAP3K5 MAPK9
Entrez ID		142679
HPRD ID		13254
Ensembl ID		ENSG00000162999
Uniprot IDs		Q8WTR2
PDB IDs		3S4E
Enriched GO Terms of Interacting Partners?		JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade MAPK Cascade Signal Transduction By Phosphorylation Activation Of JUN Kinase Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of JUN Kinase Activity Positive Regulation Of Neuron Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Cell Death Regulation Of MAPK Cascade Regulation Of JUN Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Phosphorylation Zymogen Activation Toll-like Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Innate Immune Response Positive Regulation Of JNK Cascade Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Tumor Necrosis Factor Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Endopeptidase Activity Positive Regulation Of Phosphorylation Innate Immune Response-activating Signal Transduction Response To UV Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Activation Of Innate Immune Response Positive Regulation Of Protein Modification Process Positive Regulation Of Peptidase Activity Apoptotic Process Programmed Cell Death Cell Death
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