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ACVR1C
Gene Name
activin A receptor, type IC
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Activin Receptor Complex
Molecular Function
Receptor Signaling Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta-activated Receptor Activity
ATP Binding
Activin Receptor Activity, Type I
Growth Factor Binding
Nodal Binding
Metal Ion Binding
Biological Process
Response To Dietary Excess
Protein Phosphorylation
Response To Glucose
Lipid Storage
Signal Transduction By Phosphorylation
Cell Differentiation
Apoptotic Nuclear Changes
Response To Insulin
Nodal Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Insulin Secretion
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Chorionic Trophoblast Cell Proliferation
Pathways
Signaling by Activin
Regulation of signaling by NODAL
Signaling by NODAL
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
INHBB
TDGF1
Entrez ID
130399
HPRD ID
10608
Ensembl ID
ENSG00000123612
Uniprot IDs
Q8NER5
PDB IDs
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Hepatocyte Growth Factor Biosynthetic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Follicle-stimulating Hormone Secretion
Positive Regulation Of Follicle-stimulating Hormone Secretion
Positive Regulation Of Ovulation
Regulation Of Follicle-stimulating Hormone Secretion
Negative Regulation Of Gonadotropin Secretion
Cellular Response To Hepatocyte Growth Factor Stimulus
Regulation Of MAPK Cascade
Positive Regulation Of Protein Phosphorylation
Cellular Response To Leptin Stimulus
Response To Leptin
Positive Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Anterior/posterior Axis Specification, Embryo
Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Protein Phosphorylation
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Interleukin-6
Positive Regulation Of Cellular Protein Metabolic Process
Response To Epidermal Growth Factor
Negative Regulation Of Signaling
Activin Receptor Signaling Pathway
Response To Interleukin-6
Blood Vessel Endothelial Cell Migration
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Negative Regulation Of Cytokine Biosynthetic Process
Defense Response
Negative Regulation Of Insulin Secretion
Negative Regulation Of Peptide Secretion
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Oocyte Development
Regulation Of Apoptotic Process
Oocyte Differentiation
Regulation Of Phosphorus Metabolic Process
Embryonic Axis Specification
Regulation Of Cell Death
Positive Regulation Of Cell-matrix Adhesion
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
SMAD Protein Signal Transduction
Sprouting Angiogenesis
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Hormone Secretion
Positive Regulation Of Fibroblast Proliferation
Regulation Of Intracellular Signal Transduction
Anterior/posterior Axis Specification
Somatic Stem Cell Maintenance
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