DIS3L2

Gene Name		DIS3 like 3-5 exoribonuclease 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Polysome
	Molecular Function	3'-5'-exoribonuclease Activity Magnesium Ion Binding Ribonuclease Activity Protein Binding Poly(U) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Mitotic Nuclear Division Negative Regulation Of Cell Proliferation MiRNA Catabolic Process Stem Cell Maintenance Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Cell Division Mitotic Sister Chromatid Separation RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Polyuridylation-dependent MRNA Catabolic Process
Pathways
Drugs
Diseases
GWAS		Height ( 23563607 19570815 18391951 20189936)
Protein-protein Interactions		3 interactors: COPS6 FEZ1 VIM
Entrez ID		129563
HPRD ID		14619
Ensembl ID		ENSG00000144535
Uniprot IDs		Q8IYB7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Neuron Projection Development Bergmann Glial Cell Differentiation Cullin Deneddylation Regulation Of Cell Projection Organization Protein Deneddylation Regulation Of Neuron Differentiation Viral Process Negative Regulation Of Macroautophagy Establishment Of Mitochondrion Localization Intermediate Filament Organization Lens Fiber Cell Development Regulation Of Neurogenesis Astrocyte Development Regulation Of Cell Development Muscle Filament Sliding Actin-myosin Filament Sliding Negative Regulation Of Autophagy Lens Fiber Cell Differentiation Mitochondrion Localization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction SMAD Protein Signal Transduction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament-based Movement Regulation Of Dendrite Morphogenesis Execution Phase Of Apoptosis
Tagcloud ?		biallelic degrades deleting dicer drosha enforced enu establishing exonuclease igf2 illustrated imprinting intense let lin28 mirna nephroblastoma noting opportunity pivotal predisposition recapitulates renewal rnases thirds wilms worth wt1 wtx