RXFP2

Description		relaxin family peptide receptor 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity Protein-hormone Receptor Activity Peptide Hormone Binding
	Biological Process	Oocyte Maturation Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Male Gonad Development Hormone-mediated Signaling Pathway Negative Regulation Of Apoptotic Process
Pathways		G alpha (s) signalling events Relaxin receptors
Drugs
Diseases		46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
GWAS		Essential hypertension (time to event) ( 32589924) Glycated hemoglobin levels in type 1 diabetes ( 30674623) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Pulse pressure ( 30578418) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		2 interacting genes: INSL3 RLN2
Entrez ID		122042
HPRD ID		05976
Ensembl ID		ENSG00000133105
Uniprot IDs		Q8WXD0
PDB IDs		2M96
Enriched GO Terms of Interacting Partners?		Hormone Activity
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